🦘Cacatman's Personal Coronavirus COVID-19 Update Thread

[docrusty]

CK Levels - Muscle Involvement in COVID-19

Contributing to the ongoing exploration of the extent of neurologic involvement with SARS-CoV-2 infection, the authors explored possible muscle involvement and report findings from 351 patients with COVID-19 and 258 with influenza. Almost 1 in 4 patients had elevated CK levels, which correlated somewhat with the severity of the disease. The authors found that the frequency of elevated CK levels was similar in COVID-19 and influenza, but CK levels were lower in COVID-19 compared with influenza in both mild and severe disease.

Muscle Involvement in SARS-CoV-2 Infection

www.practiceupdate.com

Been noticing this a fair amount. Thanks for the post.

 

[cacatman]

Been noticing this a fair amount. Thanks for the post.

What levels have you been seeing? Also, have you noticed if CKMB (cardiac) is elevated also?

 

[docrusty]

What levels have you been seeing? Also, have you noticed if CKMB (cardiac) is elevated also?

Typically about 1k-3k on CK. MB levels have not noticed anything.

 

[cacatman]

COVID-19 Can Cross the Blood Brain Barrier
Not good. There’s evidence to suggest the coronavirus crosses the blood brain barrier.

The most common symptoms they observed were muscle pain, headaches, dizziness, or confusion—which tend to manifest during any viral infection, especially in older people. A few patients experienced more distinct neurological syndromes, including strokes, prolonged seizure, and a disappearing sense of smell. In at least some of the patients, especially the ones with headaches, the neurological symptoms started days before a cough and fever set in.

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

This study investigates the neurologic manifestations of patients with coronavirus disease 2019.

jamanetwork.com

Microvascular Brain Injury
Using a high-powered magnetic resonance imaging (MRI) scanner 4 to 10 times as sensitive as most common MRI scanners, the investigators examined the olfactory bulbs and brainstems of the tissue samples. They observed that both of the regions showed multiple bright and dark spots, which indicate inflammation and bleeding.

https://www.nejm.org/doi/10.1056/NEJMc2033369

Our review has shown here that severe COVID-19 infection has the potential to lead to the disruption of most physiological systems and results in various multisystemic thrombotic phenomena including acute ischemic stroke. While inflammation orchestrates its pathogenesis, the further perturbation of the coagulation system resulting in fibrinolytic shutdown likewise contributes to neurological manifestation. Furthermore, the predilection of the virus to attach to ACE2 receptors in various cells, including the vascular endothelial system, may also disrupt the renin–angiotensin system, which further contributes to stroke pathogenesis. Clearly, there is a gap in the understanding of this phenomenon, and large-scale human and animal studies are necessary, as this co-occurrence results in deleterious outcomes.

The impact of COVID-19 in the human brain is as such that millions of patients are likely to experience problems with normal functioning requiring far more psychoneuroimmunological evidence-based understanding of neurorehabilitation services that are able to overcome incipient recovery problems.

Frontiers | COVID-19 Pathophysiology Predicts That Ischemic Stroke Occurrence Is an Expectation, Not an Exception—A Systematic Review

Clinical reports of neurological manifestations associated with severe coronavirus disease 2019 (COVID-19), such as acute ischemic stroke (AIS), encephalopat...

www.frontiersin.org

 

[cacatman]

The Dark Triad and How They React to COVID-19
ie. narcissism (grandiosity, pride, egotism, lack of empathy), machiavelianism (manipulation and exploitation of others, amorality) and psychopathy (antisocial behaviour, impulsivity, selfishness, remorselessness)

402 individuals were analysed.

Narcissism and Machiavellianism suffered negatively (presumably because it limited their social contact), but sadists had felt positive re: Pandemic (because they enjoyed the suffering of others)

Machiavellianists were more fearful of contracting COVID-19.

Individuals high in narcissism and psychopathy were less likely to clean as opposed to sadists.

None had hoarding tendencies.

Is the COVID-19 pandemic even darker for some? Examining dark personality and affective, cognitive, and behavioral responses to the COVID-19 pandemic

As the COVID-19 pandemic and interventions intended to minimize its spread continue to impact daily life, personality research may help to address the different ways in which people respond to a major global health crisis. The present study assessed the ...

www.ncbi.nlm.nih.gov

 

[Tom.]

Individuals high in narcissism and psychopathy were less likely to clean as opposed to sadists.

None had hoarding tendencies.

Is the COVID-19 pandemic even darker for some? Examining dark personality and affective, cognitive, and behavioral responses to the COVID-19 pandemic

As the COVID-19 pandemic and interventions intended to minimize its spread continue to impact daily life, personality research may help to address the different ways in which people respond to a major global health crisis. The present study assessed the ...

www.ncbi.nlm.nih.gov

So no one knows how covid affects Oakley forum members?

 

[Inkkoonce]

Hmm anybody else have a family member pass away from Covid? I have had one.

 

[the_owl]

Hmm anybody else have a family member pass away from Covid? I have had one.

Zero underlying conditions?

 

[Inkkoonce]

Zero underlying conditions?

Sugar diabetes and 61 years of age

 

[cacatman]

Hmm anybody else have a family member pass away from Covid? I have had one.

Sorry to hear that. No relatives so far.

But 1 neighbour in Amman, grand uncle and aunty of close friend, grandmother of a good Oakley buddy here and my lawyer's father (in Saudi Arabia) all died.

I had a close buddy of mine here admitted to hospital for oxygen (he got out, but required supplementary oxygen for 10 more days. I had to find an oxygen concentrator for him and check on him every 2 hours), another buddy's wife who survived ICU here in Amman (there's a 50% chance of dying if you need admission to ICU here in Jordan).